Posts Tagged ‘interactions’

INTRODUCTION to Lidocaine Side Effects.

Lidocaine, administered intravenously to treat of ventricular arrhythmias, is generally well tolerated. The major side effects of Lidocaine primarily involve the central nervous system, the gastrointestinal tract and the cardiovascular system.

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USES of Lidocaine: Injectable lidocaine is used to numb an area before surgery or before another medical procedure.

HOW TO USE Lidocaine: Lidocaine is injected into the body (e.g., into a muscle or under the skin) as directed by your doctor. The dosage and location of the injection depends on your condition and response to this drug. Before using Lidocaine, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn all preparation and usage instructions in the product package in advance. If any of the information is unclear, consult your pharmacist. Learn how to store and discard needles and medical supplies safely. Consult your doctor if you need it.

SIDE EFFECTS of Lidocaine: Nausea may occur. If this effect persists or worsens, contact your pharmacist. Tell your doctor immediately if any of these unlikely but serious side effects occur: dizziness, fever, drowsiness, mental/mood changes, vision changes, ringing in the ears, tremors, numbness, headache, trouble breathing, seizures, backache.

An allergic reaction to Lidocaine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.

PRECAUTIONS: Tell your doctor your medical history, especially: heart problems (e.g., heart block, heart failure), high or low blood pressure, liver problems, kidney problems, any allergies. Lidocaine is not recommended for use if you have nerve disease or spine problems. Lidocaine may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Avoid alcoholic beverages. Depending on how and where Lidocaine is injected into the body, you may experience temporary weakness. To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position. Notify your doctor if weakness or problems with muscle control persist. Caution is advised when using Lidocaine in the elderly because they may be more sensitive to the effects of the drug. Also caution is advised when using Lidocaine in children because they may be more sensitive to the effects the drug. Tell your doctor if you are pregnant before using Lidocaine. This medication passes into breast milk. Consult your doctor before breast-feeding.

Lidocaine INTERACTIONS:
Lidocaine is not recommended for use with: arbutamine, dofetilide, pimozide, halofantrine. Tell your doctor or pharmacist of all prescription and nonprescription drugs you may use, especially: other anesthetics (e.g., bupivacaine), procainamide, cimetidine, tocainide, beta-blockers (atenolol, metoprolol,propranolol), amiodarone, mexilitine, succinylcholine, vasopressor drugs (e.g., dobutamine), ergot-type oxytocic (e.g., ergonovine). Tell your doctor if you take drugs that cause drowsiness such as: medicine for sleep, tranquilizers, anti-anxiety drugs (e.g., diazepam), sedatives, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines or tricyclics), anti- seizure drugs (e.g., carbamazepine), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine). Check the labels on all your drugs (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your doctor about the safe use of those products. This product can interfere with certain lab tests. Inform laboratory personnel that you are using this medication. Do not start or stop any medicine without doctor or pharmacist approval.

Lidocaine OVERDOSE: If overdose of Lidocaine is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include restlessness, anxiety, ringing in the ears, blurred vision, tremors; or severe dizziness or drowsiness.

NOTES: Do not share Lidocaine with others. Laboratory and/or medical tests may be performed to monitor for side effects and response to treatment.

MISSED DOSE: If the dose of Lidocaine is interrupted, contact your doctor or pharmacist immediately to establish new dosing.

STORAGE: Store Lidocaine at room temperature between 59 and 77 degrees F (15 to 25 degrees C) away from light and moisture. Discard any unused liquid.

NEUROLOGIC TOXICITY

The most common adverse effect of intravenous lidocaine is central nervous system (CNS) toxicity . The symptoms are usually mild, dose-dependent, and always resolve with a decrease in the infusion rate or discontinuation of Lidocaine. These side effects may be particularly frequent in older adults or in those with heart failure, settings in which CNS levels are increased due to a reduced volume of distribution, and in patients with significant liver impairment in whom the metabolism of lidocaine is reduced.

Tremor is a useful sign of toxicity. Other neurologic side effects include insomnia, lightheadedness or drowsiness, dysarthria and slurred speech,depression, ataxia, agitation, change in sensorium, a change in personality, nystagmus, hallucinations, memory impairment, and emotional lability.

High plasma concentrations of lidocaine can also provoke seizures that are usually generalized . This can also occur at lower drug concentrations if lidocaine is given to patients receiving oral tocainide or mexiletine, which are congeners of lidocaine.

CARDIOVASCULAR TOXICITY

Cardiac side effects are an infrequent complication of intravenous lidocaine therapy which is generally well tolerated even by patients with significant underlying heart disease. The primary cardiovascular side effects include sinus slowing, asystole, hypotension, and shock. These problems are most often associated with overdosing or with the overly rapid administration of lidocaine. The elderly and those with significant preexisting heart disease are at greatest risk.

If you are about to buy Lidocaine, we recommend you to order it in Canadian pharmacy. You’ll get qualitative medication and you will save money…

What is Zithromax?

Zithromax is an macrolide antibiotic related to erythromycin. Zithromax fights bacteria in the body.
You can buy Zithromax for treatment of many different types of infections that are caused by bacteria, such as respiratory infections, ear infections, skin infections, and also sexually transmitted diseases.

If you are about to buy Zithromax, we recommend you to order it in Canadian pharmacy. You’ll get qualitative medication and you will save money…

In children, Zithromax is used for treatment of middle ear infection, tonsillitis, pneumonia, and strep throat.

How does Zithromax work?

Zithromax capsules and suspension contain the active ingredient azithromycin, that is a type of medicine called a macrolide antibiotic. Azithromycin is also available without a brand name, as the generic medicine. Zithromax is used for treatment of infections caused by bacteria.

Zithromax works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow and increase in numbers. Zithromax therefore stops the spread of infection and kills bacteria.

Zithromax is a broad-spectrum antibiotic that is active against a wide variety of bacteria that cause different infections.

You can buy Zithromax for treatment of infections of skin or soft tissue, the upper or lower airways, or ears. It is also used for treatment of the chlamydia (sexually-transmitted infection).

To make sure the bacteria causing an infection are susceptible to Zithromax your healthcare provider may take a tissue sample, (a swab from the throat or skin).

Before you buy Zithromax.

You must know that:
Broad-spectrum antibiotics like Zithromax can sometimes cause colitis(inflammation of the bowel). That’s why if you get diarrhea that becomes severe or persistent or contains blood or mucus, either during or after taking zithromax, you should report your doctor immediately.

Zithromax capsules should not be taken with food. Take it at least one hour before or two hours after food. However Zithromax suspension can be taken with food.

Taking antibiotics can sometimes lead to overgrowth of organisms that are not susceptible to the antibiotic such as fungi.

You should let your doctor know if you think you have developed any other infections while you are taking Zithromax, so that they can be treated appropriately.

It is very important that you finish the prescribed course of Zithromax, even if you feel better or it seems the infection has cleared up. Stopping the course of Zithromax early increases the chance that the infection will come back and that the bacteria will grow resistant to Zithromax.

If you have any of the following conditions, you may need a dose adjustment or special tests to safely use Zithromax: kidney disease; a heart rhythm disorder; liver disease; Long QT syndrome; myasthenia gravis.

Zithromax interactions

Do not buy Zithromax if you have ever had any allergic reactions to azithromycin or erythromycin, Biaxin (clarithromycin), Ketek (telithromycin) or troleandomycin.

Interactions of Zithromax with following medications were mentioned: cyclosporine (Neoral, Sandimmune); digoxin (Lanoxin, Lanoxicaps); triazolam (Halcion); pimozide (Orap); carbamazepine (Carbatrol, Tegretol); warfarin (Coumadin); phenytoin (Dilantin);theophylline (Theo-Dur, Theolair, Theochron); a calcium channel blocker such as diltiazem (Cartia, Cardizem), nifedipine (Procardia, Nifedical), verapamil ( Covera, Isoptin, Calan, Verelan), felodipine (Plendil),and others; ergot medicine such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Ercaf, Cafergot, Wigraine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray); cholesterol-lowering medicines such as atorvastatin (Lipitor), lovastatin (Mevacor), or simvastatin (Zocor); HIV medicines such as nelfinavir (Viracept), ritonavir (Norvir) or saquinavir (Invirase).

There are many other medicines that can have interactions with Zithromax. Tell your pharmacist about all the prescription and over-the-counter drugs you use. This includes minerals, vitamins, herbal products, and drugs prescribed by other doctors. Do not start using Zithromax without telling your doctor.

If you buy Zithromax, take it for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Don’t buy Zithromax to treat a viral infection such as the common cold or flu.

Take Zithromax capsules on an empty stomach one hour before or two hours after a meal. Zithromax tablets or powder oral suspension may be taken with or without food.

Avoid taking antacids that contain aluminum or magnesium within two hours before or after you take Zithromax. This includes Rolaids, Mylanta, Milk of Magnesia, Maalox, Pepcid Complete, and others. These antacids can make Zithromax less effective when taken at the same time.

Zithromax and pregnancy.
FDA pregnancy category B. Zithromax is not expected to be harmful to an unborn baby. Tell your pharmacist if you are pregnant or plan to become pregnant during Zithromax treatment. It is not known whether azithromycin passes into breast milk or if it could harm a nursing baby. Do not buy zithromax without telling your doctor if you are breast-feeding a baby.

Take Zithromax exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than it was prescribed by your doctor. The dose and length of treatment with Zithromax may not be the same for every type of infection.

Take each tablet or capsule with a full glass of water.

If you use the oral suspension of Zithromax, Open the packet and pour the medicine into 2 ounces of water. Stir this mixture and drink all of it. Do not save for later use. Throw away any mixed Zithromax oral suspension that has not been used within twelve hours.

To be sure you get the entire dose of Zithromax, add a little more water to the same glass, swirl gently and drink right away.

Zithromax Dosage for Bacterial Infections
The recommended Zithromax dosage for most types of common bacterial infections is 250 mg or 500 mg once a day for 3-5 days. For chronic or more serious infections, your doctor may continue treatment for an extended period.

In children, the dosage can range (depending on body weight) from 5 mg to 20 mg per kilogram of body weight per day (mg/kg/day), once a day for 3-5 days.

Zithromax Dosage for Sexually Transmitted Diseases

The recommended dose of Zithromax for the treatment of sexually transmitted diseases (STDs) is 1 gram (1000 mg) to 2 grams (2000 mg) given one time only.

Zithromax capsules must be taken on an empty stomach. Zithromax tablets or oral suspension may be taken with or without food. Take the Zithromax tablet or oral suspension with food if the medicine upsets your stomach.

Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the proper dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your healthcare provider for one.

Avoid exposure of Zithromax to sunlight or artificial UV rays (sunlamps or tanning beds). Zithromax can make your skin more sensitive to sunlight and this can lead to sunburns. Use a sunscreen (minimum SPF 15) and wear protective clothing if you plan to be out in the sun.

Zithromax side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Zithromax: difficulty breathing; hives; swelling of your face, tongue, lips, or throat. Report your doctor immidiatly if you have a serious side effect such chest pain, uneven heartbeats; diarrhea that is watery or bloody; stomach pain or upset; sore throat, fever, and headache with a severe blistering, peeling, and red skin rash; nausea, low fever, loss of appetite, dark urine, clay-colored stools, stomach pain, jaundice (yellowing of the skin or eyes);

Less serious Zithromax side effects may include: vaginal itching or discharge; dizziness, tired feeling, or headache; mild itching or skin rash; mild nausea, vomiting, diarrhea, constipation; nervous feeling, sleep disorders (insomnia); decreased sense of taste or smell; ringing in your ears, problems with hearing.

If you are about to buy Zithromax, we recommend you to order it in Canadian pharmacy. You’ll get qualitative medication and you will save money…