Among side effects of antabuse multiple cases of hepatitis were mentiond. They included both fulminant and cholestatic hepatitis.

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In a small number of patients, a transient mild drowsiness, allergic dermatitis, impotence, fatigability, headache, acneform eruptions, or a garlic-like aftertaste may be experienced during the first few weeks of therapy. These complaints usually disappear with the continuation of therapy, or with reduced dosage of antabuse.
Some possible skin eruptions are, as a rule, readily controlled by concomitant administration of an antihistaminic drug.

Antabuse may also cause headache, restlessness, drowsiness, skin rash, acne, changes in vision. Inform your doctor if any of these effects persist or worsen. Unlikely to occur but report immediately: dark urine, tingling hands or feet, weakness, strong stomach pains, fatigue, vomiting, loss of appetite, nausea, yellowing of the eyes or skin.

Psychotic reactions have been noted, attributable in most cases to high dosage of antabuse, combined toxicity (with isoniazid or metronidazole), or to the unmasking of underlying psychoses in patients stressed by the alcohol withdrawal.

Optic neuritis, polyneuritis, peripheral neuritis or peripheral neuropathy may occur when using antabuse.

It may be necessary to adjust the dosage of oral anticoagulants upon beginning or stopping antabuse, since disulfiram may prolong prothrombin time.

Anyway, you should pay attention to any other side effects that may occur, while you are using Anabuse, contact you doctor at once, if you are not sure about how does your body react to antabuse.

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